ABSTRACT
The COVID-19 vaccine has been made available for emergency use in Bangladesh. However, willingness to receive the vaccine may be affected by varying factors across the country. Therefore, this study aimed to investigate the factors that influence willingness to receive the vaccine among Bangladeshi adults. A population-based cross-sectional online survey was conducted among a sample of 1,725 Bangladesh adults (age 18 years and older). The statistical analysis included univariate, bivariate and multivariate regression model. Findings show that 85% (n = 1463) of respondents were willing to receive the vaccine. Respondents with 1–2 children (aOR: 1.77, 95% CI: 1.00–3.13, P =. 048), perceived risk of being infected (aOR: 1.48, 95% CI: 1.03–2.14, P =. 03), perceived impact on daily life (aOR: 2.53, 95%CI: 1.45–4.44, P =. 001), history of co-morbidities (aOR: 2.04, 95% CI: 1.37–3.04, P <. 01), price of the vaccine (aOR: 3.58, 95% CI: 2.34–5.47), physician’s recommendation to receive vaccine (aOR: 2.06, 95% CI: 1.38–3.06, P <. 01), vaccines supplied by government (aOR: 2.31, 95% CI: 1.64–3.25, P <. 01) were found to be motivating factors for willingness to receive the vaccine. Findings indicate that willingness to receive the vaccine is likely to be affected by socio-demographic, and health system factors. This should be carefully considered in the rollout of the vaccination plans in Bangladesh. © 2021 SAGE Publications.
ABSTRACT
Providing appropriate care for people suffering from COVID-19, the disease caused by the pandemic SARS-CoV-2 virus, is a significant global challenge. Many individuals who become infected may have pre-existing conditions that may interact with COVID-19 to increase symptom severity and mortality risk. COVID-19 patient comorbidities are likely to be informative regarding the individual risk of severe illness and mortality. Determining the degree to which comorbidities are associated with severe symptoms and mortality would thus greatly assist in COVID-19 care planning and provision. To assess this we performed a meta-analysis of published global literature, and machine learning predictive analysis using an aggregated COVID-19 global dataset. Our meta-analysis suggested that chronic obstructive pulmonary disease (COPD), cerebrovascular disease (CEVD), cardiovascular disease (CVD), type 2 diabetes, malignancy, and hypertension as most significantly associated with COVID-19 severity in the current published literature. Machine learning classification using novel aggregated cohort data similarly found COPD, CVD, CKD, type 2 diabetes, malignancy, and hypertension, as well as asthma, as the most significant features for classifying those deceased versus those who survived COVID-19. While age and gender were the most significant predictors of mortality, in terms of symptom-comorbidity combinations, it was observed that Pneumonia-Hypertension, Pneumonia-Diabetes, and Acute Respiratory Distress Syndrome (ARDS)-Hypertension showed the most significant associations with COVID-19 mortality. These results highlight the patient cohorts most likely to be at risk of COVID-19-related severe morbidity and mortality, which have implications for prioritization of hospital resources.